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human urine samples from healthy donors and kidney disease patients  (ReproCELL)
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ReproCELL human urine samples from healthy donors and kidney disease patients
(A) Presence of PTENK27-polyUb in human serum samples from healthy donors, type <t>1</t> <t>diabetic</t> patients, type 2 diabetic patients, or patients with <t>DKD</t> (n = 16, 12, 13, 13 serum samples, respectively; 1-way ANOVA). (B) Pearson’s correlation of serum PTENK27-polyUb with eGFR (n = 54 serum, Pearson χ2 test). (C) Pearson’s correlation of serum PTENK27-polyUb with eGFR of DKD patients (n = 13 serum, Pearson χ2 test). (D) ROC curves for analytes in serum PTENK27-polyUb for the diagnosis of DKD patients. (E) Pearson’s correlation of serum PTENK27-polyUb with blood glucose level in patients with type 1/2 diabetes and DKD (n = 38 serum, Pearson χ2 test). (F–G) Representative images (F) and statistical analysis of immunofluorescence staining of MEX3C (G, left) and PTENK27-polyUb (G, right) and in kidney tissues of healthy donors and DKD patients. Error bar indicates SD of staining intensities of 6 random fields per tissue (n = 9 and 9, respectively; Student’s t test). Scale bars: 100 μm. (H) Pearson’s correlation of MEX3C and PTENK27-polyUb in human kidney tissues (n = 18, Pearson χ2 test). (I) Measurement of PTENK27-polyUb concentration in human urine samples from healthy donors or DKD patients (n=10 and 6 urine samples), Error bars, SD, Student’s t-test. (J) Pearson’s correlation of urine PTENK27-polyUb with eGFR of healthy and DKD patients (n=16 urine samples, Pearson χ2 test). (K) Measurement of PTENK27-polyUb concentration in paired serum and urine samples of healthy donors, type 2 diabetes patients, and DKD patients (n = 11, Pearson χ2 test). NS indicates P > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.
Human Urine Samples From Healthy Donors And Kidney Disease Patients, supplied by ReproCELL, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/sample%2C+human+urine%2C+kidney+disease/pmc06391108-656-10-34?v=ReproCELL
Average 90 stars, based on 1 article reviews
human urine samples from healthy donors and kidney disease patients - by Bioz Stars, 2026-07
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(A) Presence of PTENK27-polyUb in human serum samples from healthy donors, type 1 diabetic patients, type 2 diabetic patients, or patients with DKD (n = 16, 12, 13, 13 serum samples, respectively; 1-way ANOVA). (B) Pearson’s correlation of serum PTENK27-polyUb with eGFR (n = 54 serum, Pearson χ2 test). (C) Pearson’s correlation of serum PTENK27-polyUb with eGFR of DKD patients (n = 13 serum, Pearson χ2 test). (D) ROC curves for analytes in serum PTENK27-polyUb for the diagnosis of DKD patients. (E) Pearson’s correlation of serum PTENK27-polyUb with blood glucose level in patients with type 1/2 diabetes and DKD (n = 38 serum, Pearson χ2 test). (F–G) Representative images (F) and statistical analysis of immunofluorescence staining of MEX3C (G, left) and PTENK27-polyUb (G, right) and in kidney tissues of healthy donors and DKD patients. Error bar indicates SD of staining intensities of 6 random fields per tissue (n = 9 and 9, respectively; Student’s t test). Scale bars: 100 μm. (H) Pearson’s correlation of MEX3C and PTENK27-polyUb in human kidney tissues (n = 18, Pearson χ2 test). (I) Measurement of PTENK27-polyUb concentration in human urine samples from healthy donors or DKD patients (n=10 and 6 urine samples), Error bars, SD, Student’s t-test. (J) Pearson’s correlation of urine PTENK27-polyUb with eGFR of healthy and DKD patients (n=16 urine samples, Pearson χ2 test). (K) Measurement of PTENK27-polyUb concentration in paired serum and urine samples of healthy donors, type 2 diabetes patients, and DKD patients (n = 11, Pearson χ2 test). NS indicates P > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

Journal: The Journal of Clinical Investigation

Article Title: PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease

doi: 10.1172/JCI121987

Figure Lengend Snippet: (A) Presence of PTENK27-polyUb in human serum samples from healthy donors, type 1 diabetic patients, type 2 diabetic patients, or patients with DKD (n = 16, 12, 13, 13 serum samples, respectively; 1-way ANOVA). (B) Pearson’s correlation of serum PTENK27-polyUb with eGFR (n = 54 serum, Pearson χ2 test). (C) Pearson’s correlation of serum PTENK27-polyUb with eGFR of DKD patients (n = 13 serum, Pearson χ2 test). (D) ROC curves for analytes in serum PTENK27-polyUb for the diagnosis of DKD patients. (E) Pearson’s correlation of serum PTENK27-polyUb with blood glucose level in patients with type 1/2 diabetes and DKD (n = 38 serum, Pearson χ2 test). (F–G) Representative images (F) and statistical analysis of immunofluorescence staining of MEX3C (G, left) and PTENK27-polyUb (G, right) and in kidney tissues of healthy donors and DKD patients. Error bar indicates SD of staining intensities of 6 random fields per tissue (n = 9 and 9, respectively; Student’s t test). Scale bars: 100 μm. (H) Pearson’s correlation of MEX3C and PTENK27-polyUb in human kidney tissues (n = 18, Pearson χ2 test). (I) Measurement of PTENK27-polyUb concentration in human urine samples from healthy donors or DKD patients (n=10 and 6 urine samples), Error bars, SD, Student’s t-test. (J) Pearson’s correlation of urine PTENK27-polyUb with eGFR of healthy and DKD patients (n=16 urine samples, Pearson χ2 test). (K) Measurement of PTENK27-polyUb concentration in paired serum and urine samples of healthy donors, type 2 diabetes patients, and DKD patients (n = 11, Pearson χ2 test). NS indicates P > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

Article Snippet: Human serum samples from healthy donors and patients with diabetic kidney disease (DKD), human urine samples from healthy donors and kidney disease patients, and paired serum/urine samples from the same patients were purchased from ReproCELL.

Techniques: Biomarker Discovery, Immunofluorescence, Staining, Concentration Assay